Sökning: "Ketamine"

Visar resultat 1 - 5 av 26 avhandlingar innehållade ordet Ketamine.

  1. 1. Neonatal Exposure to Anaesthesia and Adjuvants : Acute Effects on Cerebral Apoptosis and Neuroproteins, and Late  Behavioural Aberrations in Mice

    Författare :Emma Pontén; Anders Fredriksson; Torsten Gordh; Steen Henneberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anaesthesia; neonatal; apoptosis; bahaviour; clonidine; ketamine; propofol; theophyllamine; Medicin; Medicine;

    Sammanfattning : During a finite developmental phase – the brain growth spurt – the brain grows and matures at an accelerated rate. During this period the brain is more sensitive to harmful substances such as ethanol and environmental toxins than before or after. LÄS MER

  3. 2. Low-Dose Ionizing Radiation Induces Neurotoxicity in the Neonate : Acute or fractionated doses and interaction with xenobiotics in mice

    Författare :Sonja Buratovic; Per Eriksson; Henrik Viberg; Bo Stenerlöw; Anders Fredriksson; Jean-René Jourdain; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ionizing radiation; Neonatal; Neurotoxicity; Behaviour; Nicotine; Ketamine; Mouse; Cognition; Acute irradiation; Fractionated irradiation;

    Sammanfattning : This thesis examines the developmental neurotoxic effects of exposure to low-dose ionizing radiation (IR), alone or together with xenobiotics, during a critical period of neonatal brain development in mice.During mammalian brain development there is a period called the brain growth spurt (BGS), which involves extensive growth and maturation of the brain. LÄS MER

  4. 3. Effects of S(+)-, R(-)- and racemic ketamine on the brain

    Författare :Anders Schmidt; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Racemic ketamine, introduced in the mid-sixties, contains equal proportions of the enantiomersS(+)- and R(–)-ketamine. Early clinical reports indicated unfavourable effectson intracranial pressure (ICP) and on the cerebral circulation. Current literature on thistopic is however sparse, and available reports are divergent. LÄS MER

  5. 4. Low dose ketamine : analgesia and side-effects in patients and volunteers

    Författare :Jan Persson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : There is a need for novel approaches in the pharmacological treatment of pain. In many pain states the present treatment options are insufficient. Altered processing in sensory pathways often underlies such intractable pain. LÄS MER

  7. 5. In vivo and in vitro studies of the serotonin 1B receptor in relation to major depressive disorder and treatment with ketamine

    Författare :Emma R Veldman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite the large implications of Major Depressive Disorder (MDD) on disease burden worldwide, current treatment options are suboptimal and a third of patients suffering from this disease do not respond to treatment. Therefore, an unmet need exists for the development of new treatment options and methods to aid appropriate treatment selection in individual patients. LÄS MER