Sökning: "Kerstin Hamrin"

Hittade 1 avhandling innehållade orden Kerstin Hamrin.

1. 1. The human skeletal muscle in vivo : the use of microdialysis to study glucose metabolism and insulin resistance

   Författare :Kerstin Hamrin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Microdialysis; human skeletal muscle; glucose; lactate; pyruvate; glycerol; urea; dextran; vanadate; one-legged exercise;

   Sammanfattning : The aim of this thesis was to further develop the microdialysis technique for studies of glucose metabolism and insulin resistance in human skeletal muscle in vivo and to use this technique to explore the effect of exercise on muscle glucose metabolism and insulin action. The first two studies were conducted to explore the possibility of using a perfusion flow rate low enough to obtain complete equilibrium between the interstitial and perfusion fluids and if the colloid included in the perfusion fluid for this purpose affected the metabolite concentrations in the dialysate. LÄS MER