Sökning: "Kerstin Håkansson"

Hittade 3 avhandlingar innehållade orden Kerstin Håkansson.

  1. 1. Regulation of signal transduction in the striatum by typical and atypical antipsychotic drugs

    Författare :Kerstin Håkansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adenosine A2A receptor; basal ganglia; cAMP-dependent protein kinase; clozapine; DARPP-32; dopamine D 2 receptor; extracellular signal-regulated protein kinases 1 and 2; extrapyramidal side effects; glutamate AMPA receptor; haloperidol; knockout mouse; phosphorylation; schizophrenia; tyrosine hydroxylase.;

    Sammanfattning : The only effective therapy for schizophrenia is based on the use of antipsychotic drugs. These substances act as dopamine D 2 receptor antagonists and can be classified as typical or atypical. Typical antipsychotics, e.g. LÄS MER

  3. 2. Catalysis and Site-Specific Modification of Glutathione Transferases Enabled by Rational Design

    Författare :Sofia Håkansson Hederos; Lars Baltzer; Kerstin Broo; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Catalysis; Glutathione Transferases; Rational design; Protein design; Site-specific modification; thiolester hydrolysis; Enzyme engineering; Enzymteknik;

    Sammanfattning : This thesis describes the rational design of a novel enzyme, a thiolester hydrolase, derived from human glutathione transferase (GST) A1-1 by the introduction of a single histidine residue. The first section of the thesis describes the design and the determination of the reaction mechanism. LÄS MER

  4. 3. FE/MALE asymmetries of gender and sexuality

    Författare :Ann Kroon; Kaj Håkansson; Kerstin Sandell; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Sociology; transsexualism; gender; sexuality; masculinity; femininity; asymmetries; gender order; Sociologi; Sociologi; Sociology;

    Sammanfattning : This thesis elicits logic of gender and sexuality from modern written material on psychiatric assessment of transsexualism in Sweden. Asymmetries of gender and sexuality with regard to females vs. males are analysed. LÄS MER