Sökning: "KcsA"

Hittade 2 avhandlingar innehållade ordet KcsA.

1. 1. Exploring Ligand Binding in HIV-1 Protease and K+ Channels Using Computational Methods

   Författare :Fredrik Österberg; Johan Åqvist; Olle Edholm; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; hERG; KcsA; AutoDock; LIE; molecular dynamics; ion channels; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

   Sammanfattning : Understanding protein-ligand interactions is highly important in drug development. In the present work the objective is to comprehend the link between structure and function using molecular modelling. LÄS MER

3. 2. Molecular mechanisms of local anaesthetic action on voltage-gated ion channels

   Författare :Johanna Nilsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : In this thesis I try to clarify some molecular mechanisms of local anaesthetic action on ion channels. The traditional view is that local anaesthetics eliminate action potentials by a direct block of Na channels. Other mechanisms, however, have been suggested. LÄS MER