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1. 1. The role of CTLA-4 in health and autoimmune disease

   Författare :Katrin Klocke; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : FOXP3+ regulatory T (Treg) cells are powerful regulators of the immune system, as shown by the development of multi-organ autoimmunity in mice and men upon loss or dysfunction of these cells. Whilst Treg cells are vital to control normal immune responses, they are also involved in the development of autoimmunity and the failure to combat cancer. LÄS MER