Sökning: "Karolina Kauppi"

Hittade 2 avhandlingar innehållade orden Karolina Kauppi.

1. 1. Genes to remember : imaging genetics of hippocampus-based memory functions

   Författare :Karolina Kauppi; Lars Nyberg; Jonas Persson; Guillén Fernández; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Imaging genetics; fMRI; Episodic memory; SNP; KIBRA; BDNF; APOE; Hippocampus; Parahippocampus;

   Sammanfattning : In the field of imaging genetics, brain function and structure are used as intermediate phenotypes between genes and cognition/diseases to validate and extend findings from behavioral genetics. In this thesis, three of the strongest candidate genes for episodic memory, KIBRA, BDNF, and APOE, were examined in relation to memory performance and hippocampal/parahippocampal fMRI blood-oxygen level-dependent (BOLD) signal. LÄS MER

3. 2. The genetics of schizophrenia : sex, drugs, and cognition

   Författare :Elise Koch; Karolina Kauppi; Lars Nyberg; Anders Lundquist; Alessandro Serretti; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; schizophrenia; genetics; cognition; sex differences; polygenic risk; fMRI; network medicine; drug repurposing; precision medicine;

   Sammanfattning : Cognitive impairment constitutes an important predictor of general functional outcomes in schizophrenia. Polygenic risk for schizophrenia has been linked to cognitive ability as well as brain activation during cognitive processing. LÄS MER