Sökning: "Kaplan-Meier curves"

Visar resultat 11 - 15 av 15 avhandlingar innehållade orden Kaplan-Meier curves.

  1. 11. Studies as a basis for a possible introduction of newborn screening for cystic fibrosis in Sweden

    Författare :Isabelle de Monestrol; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Cystic fibrosis (CF) is the most common life-shortening autosomal recessive disease in Caucasians. It is a multi-organ disease that results from mutations in the gene that encodes the CF transmembrane conductance regulator (CFTR) protein, which regulates ion transport at epithelial surfaces. LÄS MER

  3. 12. Cancer associated fibroblasts and T cells in pancreatic cancer : an immune perspective

    Författare :Laia Gorchs; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : About 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC) and its deadly hallmarks, including a prominent fibrotic stroma, low mutational burden, lack of early diagnosis and rapid metastasis, contribute to trial failures and to the poor five-year overall survival rate of only 9%. Carcinoma associated fibroblasts (CAFs) are the most abundant cell type in the stroma of PDAC and their interactions with tumor cells leading to tumor progression have been extensively studied. LÄS MER

  4. 13. Studies in health economics : modelling and data analysis of costs and survival

    Författare :Mattias Ekman; Handelshögskolan i Stockholm; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : This dissertation consists of six essays in health economics.The first essay, “Economic evaluations in health care: Basic principles and special topics”, serves as an introduction to economic evaluations in health care, including estimations of costs, health effects, and the discount rate. LÄS MER

  5. 14. Factors influencing outcome in patients with obstructive hypertrophic cardiomyopathy - Effects of pharmacotherapy, pacing and surgical myectomy

    Författare :Davood Javidgonbadi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hypertrophic obstructive cardiomyopathy; myectomy; pacing; beta-blocker; survival; sex; re-intervention rate;

    Sammanfattning : Background: Most studies on risk factors for disease-related mortality in hypertrophic cardiomyopathy (HCM) have emanated from specialized tertiary centres which are subject to possible referral bias. About one quarter of HCM-patients have outflow obstruction in the left ventricle, hypertrophic obstructive cardiomyopathy (HOCM). LÄS MER

  7. 15. Liver metastases from colorectal cancer

    Författare :Jennie Engstrand; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Introduction: Colorectal cancer (CRC) is the third most common cancer worldwide. At diagnosis of CRC 20-25% of patients have metastatic disease. The liver is the most common metastatic site and liver metastases are detected in 25-30% of all patients. LÄS MER