Sökning: "Jurkat cells"
Visar resultat 11 - 15 av 39 avhandlingar innehållade orden Jurkat cells.
11. Characterization and environmental influences on inflammatory and physiological responses
Sammanfattning : Pharmaceuticals are regularly released into the environment, in particular nonsteroidalanti-inflammatory drugs (NSAIDs) and antibiotics. The measuredconcentrations are relatively low and have therefore been considered to be harmless. LÄS MER
12. Regulatory aspects of innate immune responses
Sammanfattning : Activation of innate immunity is regulated by a variety of signaling molecules within the immune cells. The present thesis was aimed to improve our understanding of innate signaling mechanism and their possible use as bio-indicators of exposure and disease. LÄS MER
13. Genetic and immunological control of human myasthenia gravis
Sammanfattning : Myasthenia gravis (MG) is a classical autoimmune disease characterized by muscle weakness due to an immune attack against the nicotinic acetylcholine receptor (AChR) on the post-synaptic membrane of the neuromuscular junction. Because of the involvement of multiple factors in the disease, the overall aims of this thesis were to uncover the regulation of candidate genes and the possible cellular mechanisms involved in the immuno-regulation of human MG. LÄS MER
14. B cell activation in vitro: thymus-dependent immune responses and bacterial cell surface proteins
Sammanfattning : In this thesis aspects of peripheral B lymphocyte differentiation were studied. Through in vitro experiments, B lymphocyte activation was assessed. B lymphocytes express immunoglobulin (Ig) specific for a certain antigen on the cell surface, and when surface Ig is crosslinked by an antigen, the cell is activated. LÄS MER
15. Regulation of T-cell proliferation and B-CLL apoptosis by CD6 and FAS/FASL
Sammanfattning : T-cell activation involves the interaction between the T-cell receptor (TCR) and the peptide/MHC complex presented on an antigen-presenting cell. However, this is not sufficient for the full development of T cell responses and co-stimulatory signals from accessory molecules are required. LÄS MER