Sökning: "Julien Menard"

Hittade 1 avhandling innehållade orden Julien Menard.

1. 1. Adaptive mechanisms in the hypoxic tumor microenvironment. Functional role of proteoglycans and identification of potential treatment targets

   Författare :Julien Menard; Tumörmikromiljö; []
   Nyckelord :Hypoxia; Acidosis; Proteoglycans; Endocytosis; Glioblastoma; Lipid; Caveolin-1; Antibody-drug conjugate;

   Sammanfattning : Cancer cells reside in a complex microenvironment comprising stromal cells and immune cells embedded in an extracellular matrix (ECM). Early on in tumor progression, cells reach a critical volume beyond which blood supply is impaired, leading to a decrease in oxygen levels (hypoxia) and nutrient supply. LÄS MER