Sökning: "Julia König"

Hittade 3 avhandlingar innehållade orden Julia König.

  1. 1. Gut microbiota, its modifications and the gut-brain axis

    Författare :Julia Rode; Robert Jan Brummer; Julia König; Mirjana Rajilic-Stojanovic; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gut microbiota; gut-brain axis; faecal microbiota transfer; probiotics; butyratFunctional magnetic resonance imaging; mental health; collagenous colitis;

    Sammanfattning : The human intestinal microbiota has a major impact on host physiology and might play an important role in several diseases. Therapeutic interventions aimed at modifying the gut microbiota might exert their effects locally as well as systemically, for example via the gut-brain axis, a bidirectional communication system. LÄS MER

  3. 2. Faecal Microbiota Transfer in Irritable Bowel Syndrome and Collagenous Colitis : Clinical outcomes and host-microbe interactions

    Författare :Savanne Holster; Robert Jan Brummer; Julia König; Andreas Munk Petersen; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Faecal microbiota transfer; irritable bowel syndrome; collagenous colitis; gut microbiota; visceral sensitivity; host-microbe interactions; gene expression; metabolites;

    Sammanfattning : Faecal microbiota transfer (FMT) aims at restoring a disturbed gut microbiotaby introducing faecal material from a healthy donor into a patient’s intestine. This approach is known as a safe and effective treatment in patients with recurrent Clostridioides difficile infection. LÄS MER

  4. 3. Challenge models and biomarkers of human intestinal barrier function

    Författare :María Fernanda Roca Rubio; Julia König; Robert J Brummer; Richard Forsgård; Kaatje Lenaerts; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacterial translocation; biomarkers; challenge models; intestinal barrier function; intestinal permeability; irritable bowel syndrome; physiological stress; psychological stress;

    Sammanfattning : The intestinal barrier is an essential component in maintaining human health, and several diseases and disorders have been associated with a disrupted intestinal barrier function. To evaluate the efficacy of different interventions intended to strengthen intestinal barrier function, there is a need for both appropriate challenge models as well as easily accessible biomarkers. LÄS MER