Sökning: "Joshua Rosenthal"

Hittade 2 avhandlingar innehållade orden Joshua Rosenthal.

  1. 1. Regulation and Function of RNA Editing in the Mammalian Brain

    Författare :Chammiran Daniel; Marie Öhman; Joshua Rosenthal; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA editing; ADAR; GABAA receptor; Gabra-3; Molecular Biology; molekylärbiologi;

    Sammanfattning : Adenosine (A) to inosine (I) RNA editing is a widespread post-transcriptional mechanism in eukaryotes that increases the protein diversity. Adenosine deaminases acting on RNA (ADARs) are the enzymes that catalyze this conversion. LÄS MER

  3. 2. Diversifying the transcriptome : Adenosine-to-inosine RNA editing in the mammalian brain

    Författare :Albin Widmark; Neus Visa; Joshua Rosenthal; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA editing; ADAR; microRNA; brain development; neuron; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Metazoan transcriptomes are extensively modified by adenosine-to-inosine (A-to-I) RNA editing, a process by which adenosines within double-stranded RNA are enzymatically deaminated to form inosines. Inosines has base-pairing characteristics similar to guanosine, meaning that A-to-I RNA editing results in functional rewriting of transcripts, affecting many biological processes. LÄS MER