Sökning: "Josefine Larsson"

Hittade 2 avhandlingar innehållade orden Josefine Larsson.

  1. 1. Genetic Aspects of Environmental Disturbances in Marine Ecosystems : Studies of the Blue Mussel in the Baltic Sea

    Författare :Josefine Larsson; Mats Grahn; Inger Porsch-Hällström; Katarzyna Smolarz; Andrew Whitehead; Södertörns högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Blue mussel; Baltic Sea; anthropogenic disturbance; pollution; sewage effluents; harbors; genetics; genomics; Environmental Studies; Miljövetenskapliga studier; Östersjö- och Östeuropaforskning; Baltic and East European studies;

    Sammanfattning : Anthropogenic environmental changes can serve as drivers for evolutionary responses in wild populations. To predict the long-term impact of anthropogenic changes on populations, it is crucial to understand the genetic effects caused by these disturbances. LÄS MER

  3. 2. Optimizing Chemotherapy in Childhood Acute Myeloid Leukemia

    Författare :Josefine Palle; Gudmar Lönnerholm; Britt-Marie Frost; Rolf Larsson; Henrik Schröder; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; childhood; acute myeloid leukemia; drug resistance; pharmacokinetics; chromosomal abnormalities; Down syndrome; MLL-rearrangement; t 9; 11 ; Paediatric medicine; Pediatrisk medicin;

    Sammanfattning : Despite major advances in our understanding of the biology of childhood acute myeloid leukemia (AML) and the development of new cytotoxic drugs, the prognosis of long-term survival is still only 60-65 %.In the present research, we studied the pharmacokinetics of drugs used in the induction therapy of childhood AML and performed in vitro drug sensitivity testing of leukemic cells from children with AML. LÄS MER