Sökning: "Jonas Bergquist"

Visar resultat 21 - 25 av 46 avhandlingar innehållade orden Jonas Bergquist.

  1. 21. Mass Spectrometry of Non-protein Amino Acids : BMAA and Neurodegenerative Diseases

    Författare :Liying Jiang; Leopold Ilag; Jonas Bergquist; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neurodegenerative diseases; BMAA; Isomers; LC-MS MS; Cyanobacteria; Diatoms; Seafood contamination; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Neurodegenerative diseases have been shown to correlate positively with an ageing population. The most common neurodegenerative diseases are amyotrophic lateral sclerosis (ALS), Parkinson’s disease and Alzheimer’s disease. LÄS MER

  3. 22. Column Development in Capillary Electrophoresis and Electrochromatography for Bioanalytical Applications

    Författare :Nina Johannesson; Jonas Bergquist; Karin Markides; Abdul Malik; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Capillary electrophoresis CE ; Capillary electrochromatography CEC ; Mass spectrometry MS ; Bioanalysis; Sample pretreatment; Sol-gel; Analytisk kemi;

    Sammanfattning : Analysis of biological samples can be a difficult task. This thesis covers a broad aspect of the analytical areas of capillary electrophoresis (CE) and capillary electrochromatography (CEC) in combination with mass spectrometry (MS) that are of great importance for achieving fast, accurate and sensitive bioanalyses. LÄS MER

  4. 23. Development of Methods in CE, CE-MS and MS/MS : Applications in Pharmaceutical, Biomedical and Forensic sciences

    Författare :Emmy Jäverfalk-Hoyes; Jonas Bergquist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Sammanfattning : Capillary electrophoresis-mass spectrometry has been used successfully for the analysis of a wide range of analytes such as chiral local anaesthetics, sulphonated reactive dyes and endogenous neurotransmitters and neuropeptides.The partial filling technique was used in CE-MS for chiral separation of bupivacaine and ropivacaine using the non-volatile selector β-cyclodextrin. LÄS MER

  5. 24. Inductively Coupled Plasma Atomic Emission Spectrometry : Exploring the Limits of Different Sample Preparation Strategies

    Författare :Barbro Kollander; Jean Pettersson; Marit Andersson; Jonas Bergquist; Grethe Wibetoe; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; multi element analysis; trace element; ICP-AES; inductively coupled plasma atomic emission spectromtery; water analysis; liver analysis; non digested samples; medical samples; biological samples; samples from biopsies and autopsies; mice organ; fast analysis; internal standard; preconcentration; matrix elimination; Cu; Zn; Mn; Co; Pb; Cd; Mg; Ca; Fe; Ni; Cr; S; P; K; Al; Analytical chemistry; Analytisk kemi; Analytical Chemistry; Analytisk kemi;

    Sammanfattning : This thesis describes two different sample preparation strategies for inductively coupled plasma atomic emission spectrometry (ICP-AES), and their ability regarding multi element quantification in complex samples. Sensitivity, repeatability, reproducibility and accuracy were investigated. LÄS MER

  7. 25. Mass Spectrometric Applications for Diagnosing Metabolic and Endocrine Diseases

    Författare :Mark M. Kushnir; Jonas Bergquist; Alan L Rockwood; David Herold; Uppsala universitet; []
    Nyckelord :Analytical chemistry; biomarker; liquid chromatography; tandem mass spectrometry; LC-MS MS; sample preparation; isomers; steroid hormones; congenital adrenal hyperplasia; polycystic ovary syndrome; Analytisk kemi;

    Sammanfattning : Disease-specific compounds (biomarkers) are analyzed in clinical laboratories to assist with diagnosing diseases. This thesis describes development and validation of liquid chromatography tandem mass spectrometry (LC-MS/MS) based tests for diagnosing a diverse group of endocrine and metabolic diseases. LÄS MER