Sökning: "Johan Jakobsson"
Visar resultat 6 - 10 av 14 avhandlingar innehållade orden Johan Jakobsson.
6. Cell type-specific translatome analysis of mouse models of three genetic neurodegenerative diseases
Sammanfattning : The burden neurodegenerative diseases place on patients, their loved ones, and the healthcare system is significant, and despite extensive research efforts, there is currently no cure. Since degenerative changes in the brain can begin years before symptoms appear, early intervention is critical. LÄS MER
7. Beyond Moral Teaching : Financial Literacy as Citizenship Education
Sammanfattning : This thesis explores what financial literacy is, what financial literacy becomes and what financial literacy could become within the context of a citizenship education such as the Swedish upper secondary subject of social studies. Financial literacy does not intuitively converge with social sciences which leaves social studies teachers to both teach and realise financial literacy. LÄS MER
8. On the Late Saalian glaciation : A climate modeling study
Sammanfattning : This thesis focuses on the glaciation of the Late Saalian period (160 -140 ka) over Eurasia. The Quaternary Environment of the Eurasian North (QUEEN) project determined that during this period, the Eurasian ice sheet was substantially larger than during the entire Weichselian cycle and especially that of the Last Glacial Maximum (21 ka, LGM). LÄS MER
9. Catalytic and Structural Properties of Heme-containing Fatty Acid Dioxygenases : Similarities of Fungal Dioxygenases and Cyclooxygenases
Sammanfattning : 7,8-Linoleate diol synthase (7,8-LDS) of the take-all pathogen of wheat, Gaeumannomyces graminis, converts linoleic acid to 8R-hydroperoxyoctadecadienoic acid (8-HPODE) by 8-dioxygenase activity (8-DOX), and further isomerizes the hydroperoxide to 7S,8S-dihydroxyoctadecadienoic acid (7,8-DiHODE) by hydroperoxide isomerase activity. Sequence alignment showed homology to prostaglandin H synthase (PGHS), and both enzymes share structural and catalytic properties. LÄS MER
10. Influence of depth of anesthesia on postoperative cognitive dysfunction (POCD) and inflammatory markers
Sammanfattning : Patients may suffer from various forms of postoperative cognitive dysfunction (POCD). In most cases, the impact on cognitive function is relatively transient but POCD can sometimes be long-lasting (> 1 year). Studies showing that up to one in four patients with known risk factors are affected by some form of cognitive loss. LÄS MER