Sökning: "Johan Farngren"

Hittade 1 avhandling innehållade orden Johan Farngren.

1. 1. Glucagon Counter-Regulation to Hypoglycemia During Incretin-Based Therapy

   Författare :Johan Farngren; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Incretin; DPP-4; GLP-1; Glucagon; Hypoglycemia; Diabetes;

   Sammanfattning : Incretin-based therapy is associated with low risk of hypoglycemia in type 2 diabetes mellitus (T2DM) possibly due to its glucose-dependency in stimulating insulin secretion and a sustained glucagon response during hypoglycemia. This is of special relevance when it is combined with insulin or given to elderly patients since both insulin therapy and high age are associated with impaired glucagon counter-regulation. LÄS MER