Sökning: "Johan Ahlner"

Visar resultat 6 - 10 av 12 avhandlingar innehållade orden Johan Ahlner.

  1. 6. Genetic influence on enantiomeric drug disposition : Focus on venlafaxine and citalopram

    Författare :Maria Kingbäck; Fredrik Kugelberg; Björn Carlsson; Martin Josefsson; Finn Bengtsson; Johan Ahlner; Anders Rane; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : A molecule that is not identical to its mirror image is said to be chiral. A racemic mixture, or a racemate, is one that has equal amounts of S- and R-enantiomers of a chiral molecule. Two examples of frequently prescribed racemic drugs are the antidepressants venlafaxine (VEN) and citalopram (CIT). LÄS MER

  3. 7. Testosterone Use and Abuse : Methodological Aspects in Forensic Toxicology and Clinical Diagnostics

    Författare :Yvonne Lood; Jeanette Wahlberg; Johan Ahlner; Bertil Ekman; Elisabeth Aardal; Martin Josefsson; Ingemar Thiblin; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Abuse of anabolic androgenic steroids (AAS) is widespread in society and is today a major public health problem, associated with mental and somatic adverse effects and risk behavior, such as use of other illicit drugs and criminality. Testosterone, the most important endogenous male androgen, is therapeutically used in replacement therapy but is also extensively used as a doping agent. LÄS MER

  4. 8. Stability of zopiclone in whole blood : Studies from a forensic perspective

    Författare :Gunnel Nilsson; Robert Kronstrand; Johan Ahlner; Fredrik Kugelberg; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Bio‐analytical results are influenced by in vivo factors like genetic, pharmacological and physiological conditions and in vitro factors like specimen composition, sample additives and storage conditions. The knowledge of stability of a drug and its major metabolites in biological matrices is very important in forensic cases for the interpretation of analytical results. LÄS MER

  5. 9. Zopiclone degradation in biological samples : Characteristics and consequences in forensic toxicology

    Författare :Gunnel Nilsson; Robert Kronstrand; Fredrik C. Kugelberg; Johan Ahlner; Mikael Hedeland; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Bio-analytical results are influenced by in vivo factors such as genetics, pharmacological and physiological conditions and in vitro factors such as specimen composition, sample additives and storage conditions. Zopiclone (ZOP) is a short-acting hypnotic drug (Imovane®) used for treatment of insomnia. LÄS MER

  7. 10. Psychoactive prescription drug use disorders, misuse and abuse : Pharmacoepidemiological aspects

    Författare :Micaela Tjäderborn; Staffan Hägg; Johan Ahlner; Anna Jönsson; Morten Andersen; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychoactive prescription drugs; psychotropic drugs; prescription drug use disorders; prescription drug misuse; abuse; pharmacovigilance; drug utilization; pharmacoepidemiology;

    Sammanfattning : Background: There is a widespread and increasing use of psychoactive prescription drugs, such as opioid analgesics, anxiolytics, hypnotics and anti-epileptics, but their use is associated with a risk of drug use disorder, misuse and abuse. Today, these are globally recognized and emerging public health concerns. LÄS MER