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Visar resultat 1 - 5 av 41 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Computational methods for analysis of spatial transcriptomics data : An exploration of the spatial gene expression landscape

    Författare :Alma Andersson; Joakim Lundeberg; Omer Bayraktar; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; spatial transcriptomics; machine learning; data analysis; RNA-seq; probabilistic; statistical; models; Biotechnology; Bioteknologi;

    Sammanfattning : Transcriptomics techniques, whether in the form of bulk, single cell/nuclei, or spatial methods have fueled a substantial expansion of our knowledge about the biological systems within and around us. In addition, the rate of innovation has accelerated over the last decade, resulting in a multitude of technological advances and new methods for generation of transcriptomics data. LÄS MER

  3. 2. Microarray-based investigation of genome and transcriptome organisation in the archaeon sulfolobus

    Författare :Anders Andersson; Joakim Lundeberg; Per Sunnerhagen; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; microarray; Sulfolobus; gene expression; archaea; mRNA decay; genome evolution; Bioteknik; Bioengineering; Bioteknik;

    Sammanfattning : .... LÄS MER

  4. 3. Development and application of spatial transcriptomics methods

    Författare :Zaneta Andrusivova; Joakim Lundeberg; Jay W. Shin; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA; Spatial Transcriptomics; RNA sequencing; Biotechnology; Bioteknologi;

    Sammanfattning : Transcriptomics is one of the pivotal fields in molecular biology, enabling comprehensive analysis of gene expression patterns. Recent advancements in the biotechnology field have transformed the transcriptomics research, providing insights into the complexity of cellular processes in a greater detail. LÄS MER

  5. 4. Spatially Resolved Gene Expression Analysis

    Författare :Michaela Asp; Joakim Lundeberg; Patrik Ståhl; Thierry Voet; KTH; []
    Nyckelord :RNA; RNA-sequencing; transcriptomics; spatial transcriptomics; single cells; Bioteknologi; Biotechnology;

    Sammanfattning : Spatially resolved transcriptomics has greatly expanded our knowledge of complex multicellular biological systems. To date, several technologies have been developed that combine gene expression data with information about its spatial tissue context. LÄS MER

  7. 5. Exploring the transcriptional space

    Författare :Joseph Bergenstråhle; Joakim Lundeberg; Jay W. Shin; KTH; []
    Nyckelord :Transcriptomics Spatial; Bioteknologi; Biotechnology;

    Sammanfattning : Transcriptomics promises biological insight into gene regulation, cell diversity, and mechanistic understanding of dysfunction. Driven by technological advancements in sequencing technologies, the field has witnessed an exponential growth in data output. Not only has the amount of raw data increased tremendously but it’s granularity as well. LÄS MER