Sökning: "Jiang Yiwen"

Hittade 1 avhandling innehållade orden Jiang Yiwen.

1. 1. Interplay Between Cell of Origin and Oncogenic Activation in Glioma

   Författare :Yiwen Jiang; Lene Uhrbom; Anders Persson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; PDGF; cell of origin; Sox5; glioma initiating cells; Oncology; Onkologi;

   Sammanfattning : Glioma is the most frequent primary tumor of the central nervous system. By using the RCAS/tv-a mouse glioma model, we have studied mechanisms controlling glioma development and the effect of cell of origin on these processes.SOX5 was identified as a brain tumor locus in a retroviral insertional mutagenesis screen of PDGF-B induced mouse gliomas. LÄS MER