Sökning: "Jian Qin"

Hittade 2 avhandlingar innehållade orden Jian Qin.

  1. 1. Nanoparticles for multifunctional drug delivery systems

    Författare :Jian Qin; Mamoun Muhammed; Paavo K J Kinnunen; KTH; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; drug delivery; stimuli-sensitive; SPION; PLLA; PNIPAAm; gold; MRI; cytotoxicity; Pluronic; phase transfer; Materials chemistry; Materialkemi;

    Sammanfattning : Multifunctional drug delivery systems incorporated with stimuli-sensitive drug release, magnetic nanoparticles and magnetic resonance (MR) T2 contrast agents is attracting increasing attention recently. In this thesis, works on polymer nanospheres response to temperature change, superparamagnetic iron oxide nanoparticles (SPION)/polymeric composite materials for MR imaging contrast agents are summarized. LÄS MER

  2. 2. Environment-Sensitive Multifunctional Drug Delivery Systems

    Författare :Jian Qin; Mamoun Muhammed; Marcus Textor; KTH; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Materials chemistry; Materialkemi;

    Sammanfattning : Drug delivery systems (DDS) with multiple functionalities such as environment-sensitive drug release mechanisms and visualization agents have motivated the biomedical community as well as materials chemists for more than a decade. This dissertation is concerned with the development of nanoparticles for multifunctional DDS  to tackle several crucial challenges in these complex systems, including polymeric nanospheres which respond to temperature change, superparamagnetic iron oxide nanoparticles/polymeric composite for magnetic resonance imaging contrast agents and drug carriers, immunoresponse of nanomaterials and injectable magnetic field sensitive ferrogels. LÄS MER