Sökning: "Jessica Rosenholm"

Hittade 3 avhandlingar innehållade orden Jessica Rosenholm.

  1. 1. Translational Tumor Drug Delivery : Doxorubicin formulation performance, intracellular uptake and molecular diffusion

    Författare :Oliver Degerstedt; Hans Lennernäs; Erik Sjögren; Per Hansson; Jessica Rosenholm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; doxorubicin; drug diffusion; cellular uptake; drug delivery; PBPK modelling; hepatocellular carcinoma; emulsion; IC50; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Globally, hepatocellular carcinoma (HCC) is the most common form of liver cancer and a leading cause of cancer death. One important risk factor is liver cirrhosis and the disease progression is characterized by deposition of extracellular matrix proteins that form a fibrous network, which increases liver stiffness and may limit the effectiveness of different treatment strategies. LÄS MER

  3. 2. Mesoporous Silica Particles for a Potential Therapeutic Application

    Författare :Muhammad Naeem Iqbal; Niklas Hedin; Tore Bengtsson; Mirva Eriksson; Jessica Rosenholm; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mesoporous silica; SBA-15; amylase; lipase; electron microscope; adsorption; type 2 diabetes; materialkemi; Materials Chemistry;

    Sammanfattning : Mesoporous silica particles (MSPs) have a high surface area, pore volume, and tunable pore size and surface properties, which makes them ideal for advanced therapeutic, biocatalytic, separation, and drug delivery applications. The work in this thesis shows that MSPs can be employed for therapeutic applications with minimal risk of adverse consequences. LÄS MER

  4. 3. Development of Nanoporous Inorganic Carbonates for Pharmaceutical and Environmental Applications

    Författare :Maria Vall; Ocean Cheung; Maria Strømme; Jessica Rosenholm; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Mesoporous magnesium carbonate; drug delivery; water purification; CO2 capture; catalysis; Engineering Science with specialization in Nanotechnology and Functional Materials; Teknisk fysik med inriktning mot nanoteknologi och funktionella material;

    Sammanfattning : Mesoporous magnesium carbonate (MMC) is a highly porous, anhydrous material which can be synthesized without the use of templates. This thesis shows how post- and in synthesis modification of MMC can create porous inorganic carbonates suitable for different pharmaceutical and environmental applications. LÄS MER