Sökning: "Jenny Tigerholm"

Hittade 2 avhandlingar innehållade orden Jenny Tigerholm.

  1. 1. Mechanisms of excitability in the central and peripheral nervous systems : Implications for epilepsy and chronic pain

    Författare :Jenny Tigerholm; Erik Fransén; Dieter Jaeger; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Dendritic excitability; synchronized synaptic input; multicompartment model; epilepsy; axonal excitability; silent C–fibres; Hodgkin–Huxley dynamics; conduction velocity; KA;

    Sammanfattning : The work in this thesis concerns mechanisms of excitability of neurons. Specifically, it deals with how neurons respond to input, and how their response is controlled by ion channels and other active components of the neuron. LÄS MER

  3. 2. A-type Potassium Channels in Dendritic Integration : Role in Epileptogenesis

    Författare :Jenny Tigerholm; Erik Fransén; Fredrik Elinder; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; epileptogenesis; fast ripples; synchronicity; dendritic potentials; transient A–type potassium current; KV 4.2; Computer and systems science; Data- och systemvetenskap;

    Sammanfattning : During cognitive tasks, synchronicity of neural activity varies and is correlated with performance. However, there may be an upper limit to normal synchronised activity – specifically, epileptogenic activity is characterized byexcess spiking at high synchronicity. LÄS MER