Sökning: "JanOve Sehlin"
Hittade 5 avhandlingar innehållade orden JanOve Sehlin.
1. Studies on the mechanism of amino acidinduced insulin release
Sammanfattning : .... LÄS MER
2. Properties of Endothelium and its Importance in Endogenous and Transplanted Islets of Langerhans
Sammanfattning : Transplantation of insulin producing cells is currently the only cure for type 1 diabetes. However, even though the Edmonton protocol markedly increased the success rate of pancreatic islet transplantation, the long term insulin independence is still very poor. An adequate engraftment is critical for islet graft survival and function. LÄS MER
3. On the Regulation of the Epithelial Paracellular Permeability
Sammanfattning : The epithelia of for instance the small intestine(s) plays a crucial role in the vectorial transport of nutrients and other solutes from the lumen to underlying body fluids, i.e. blood and lymph. LÄS MER
4. Glucose and insulin modulate phagocytosis and production of reactive oxygen metabolites in human neutrophil granulocytes
Sammanfattning : Neutrophil granulocytes play an important role in the host defence against invading microorganisms and constitute the frontline of defence within the innate immune system and are among the first cells to arrive at the site of inflammation. Effective phagocytosis and killing of invading pathogens by neutrophils is of significant importance for successful resistance to infectious diseases. LÄS MER
5. Studies of SIRPα-mediated regulation of neutrophil functions
Sammanfattning : Neutrophil granulocytes constitute the front line of defense in the innate immune response to invading microorganisms, but can also contribute to development of inflammatory disease and tissue destruction following e.g. myocardial infarction or stroke. LÄS MER