Sökning: "Jan-ingvar Jönsson"
Visar resultat 1 - 5 av 17 avhandlingar innehållade orden Jan-ingvar Jönsson.
1. Genetic mechanisms regulating proliferation and cell specification in the Drosophila embryonic CNS
Sammanfattning : The central nervous system (CNS) consists of an enormous number of cells, and large cellular variance, integrated into an elaborate network. The CNS is the most complex animal organ, and therefore its establishment must be controlled by many different genetic programs. LÄS MER
2. Genetic pathways controlling CNS development : The role of Notch signaling in regulating daughter cell proliferation in Drosophila
Sammanfattning : The human central nervous system (CNS) displays the greatest cellular diversity of any organ system, consisting of billions of neurons, of numerous cell sub-types, interconnected in a vast network. Given this enormous complexity, decoding the genetic programs controlling the multistep process of CNS development remains a major challenge. LÄS MER
3. Stem cell function and organ development : analysis of Lhx2 function in hematopoietic stem cells and eye development
Sammanfattning : When a multicellular organism suffers damages to tissues/organs it heals itself by either substituting the lost cellular matrix by scar formation or by regenerating the lost tissue. Regeneration likely occurs by a recapitulation of the developmental process that formed the organ. LÄS MER
4. Live and Let Die : Critical regulation of survival in normal and malignant hematopoietic stem and progenitor cells
Sammanfattning : The hematopoietic stem cell (HSC) is characterized by its ability to self-renew and produce all mature blood cells throughout the life of an organism. This is tightly regulated to maintain a balance between survival, proliferation, and differentiation. LÄS MER
5. The mitochondrial protein SLC25A43 and it's possible role in HER2-positive breast cancer
Sammanfattning : .... LÄS MER