Sökning: "Jakob Domert"

Hittade 1 avhandling innehållade orden Jakob Domert.

  1. 1. Neuron-to-neuron propagation of neurodegenerative proteins; relation to degradative systems

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Jakob Domert; Linköpings universitet.; Linköpings universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell-to-cell transfer; beta-amyloid; Alzheimer s disease; degradation; proteasome; alpha-synuclein; Parkinson s disease; high throughput screening model;

    Sammanfattning : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are defined by neurodegeneration and accumulations of misfolded proteins that spread through the brain in a well characterized manner. In AD these accumulations consist mainly of β-amyloid (Aβ) and tau, while in PD, α-synuclein (α-syn) make up the characteristic lewy pathology. LÄS MER