Sökning: "Jacobsen"

Visar resultat 1 - 5 av 41 avhandlingar innehållade ordet Jacobsen.

1. 1. Constraining the Dark Matter Parameter Space

   Författare :Sunniva Jacobsen; Katherine Freese; Ilias Cholis; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Theoretical Physics; teoretisk fysik;

   Sammanfattning : The nature of dark matter (DM) is one of the greatest mysteries of modern physics. Itmakes up 25% of the total energy-matter content in the Universe, and is essential forexplaining the large-scale structures we observe in the Universe. Little is known aboutthe nature of dark matter, and the number of possible theories is vast. LÄS MER

3. 2. Vascular endothelial growth factor in renal cell carcinoma

   Författare :Jan Jacobsen; Börje Ljungberg; Kjell Grankvist; Torgny Rasmuson; Anders Bergh; Peter Ekman; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; VEGF; isoforms; quantitative RT-PCR; immunohistochemistry; tissue microarray; Western blot; stage; survival; renal cell carcinoma; Urology and andrology; Urologi och andrologi;

   Sammanfattning : Background. Angiogenesis is essential for tumour growth. Vascular endothelial growth factor (VEGF) and its isoforms were investigated in relation to the clinical course in a large number of patients with renal cell carcinoma (RCC). Methods. LÄS MER

4. 3. Processing of the APP family by the α-secretases ADAM10 and TACE

   Författare :Kristin Jacobsen; Kerstin Iverfeldt; Lars Nilsson; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry; Neurokemi; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

   Sammanfattning : Alzheimer’s disease (AD) is a progressive neurodegenerative disease, which is characterized by formation of amyloid plaques in the brain. The major constituent of these plaques is the hydrophobic peptide Aβ. Aβ accumulation is considered to be the main cause of the pathology seen in AD brains. LÄS MER

5. 4. α-Secretase processing of the Alzheimer amyloid-β precursor protein and its homolog APLP2

   Författare :Kristin Jacobsen; Kerstin Iverfeldt; Olav Andersen; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; APP; APLP2; ADAM10; TACE; Alzheimer s Disease; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : The amyloid-β precursor protein (APP) has been widely studied due to its role in Alzheimer´s disease (AD). When APP is sequentially cleaved by β- and γ-secretase, amyloid-β (Aβ) is formed. Aβ is prone to aggregate and is toxic to neurons. LÄS MER

7. 5. On improving efficiency of flight using optimization

   Författare :Marianne Jacobsen; Ulf Ringertz; Virginia Torczon; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Vehicle engineering; Farkostteknik;

   Sammanfattning : In this thesis, optimization is used to improve the performance of aircraft. The focus is on operating current generation aircraft more efficiently rather than designing new aircraft. Drag minimization and aircraft trajectory optimization is used to increase efficiency. LÄS MER