Sökning: "Itzia Jimenez"

Hittade 1 avhandling innehållade orden Itzia Jimenez.

1. 1. Immunogenetics of Parkinson's disease: Translational studies from rodents to humans

   Författare :Itzia Jimenez; Translationell Neurogenetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genetics; inflammation; α-synuclein; dopaminergic neurons; MHCII; Mhc2ta; Vra4; PFFs; microglia;

   Sammanfattning : Parkinson's disease (PD) is a complex neurodegenerative disease, characterized by a progressive lossof dopaminergic neurons (DN) in the substantia nigra (SN) that innervate the striatum (ST) and pathologicalaccumulation of alpha-synuclein (αsyn) protein in aggregates called Lewy bodies (LB) and Lewy neurites(LN). As a complex disease, PD presents a genetically heterogeneous origin. LÄS MER