Sökning: "Isoxazoles"

Hittade 2 avhandlingar innehållade ordet Isoxazoles.

1. 1. Cyclooxygenase-2 inhibitors and knee prosthesis surgery

   Författare :Andreas Meunier; Lars Good; Per Aspenberg; Tore Dalén; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-steroidal anti-inflammatory agents; administration dosage; Arthroplasty; knee replacement; Surgical blood loss; Surgery; Cyclooxygenase inhibitors; Cyclooxygenase inhibitors; Fracture healing; Isoxazoles; Postoperative pain; Pyrazoles; Sulfonamides; Surgery; Kirurgi;

   Sammanfattning : Adverse effects of cyclooxygenase (COX) inhibitors on bone healing have previously been demonstrated in diaphyseal fracture models in animals. In spite of that, they are widely used as postoperative analgesics in orthopaedic surgery. After joint replacement, a bone repair process starts at the interface between bone and cement. LÄS MER

3. 2. Anti-Virulence Strategy Targeting Sortase A, A Structural Investigation of the Sortase A Enzyme, and the Identification, Synthesis, and Evaluation of Sortase A Inhibitors

   Författare :Ivana Uzelac; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi;

   Sammanfattning : The emergence of multi-resistant bacteria and their continuous spread is one of the greatest challenges when treating bacterial infections. Increased understanding of bacterial pathogenesis has revealed new strategies for treating bacteria-mediated diseases. LÄS MER