Sökning: "Isotope-tracing"

Hittade 5 avhandlingar innehållade ordet Isotope-tracing.

  1. 1. Nitrogen Cycling at Cold Climate Mine Sites in Northen Sweden

    Författare :Lino Nilsson; Anders Widerlund; Anders Lundqvist; Luleå tekniska universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nitrogen; Mining; Cycling; nutrients; Isotopes; Nitrogen-model; modelling; numerical-modelling; Isotope-tracing; Tracing; Isotope; geochemistry; Applied Geology; Tillämpad geologi;

    Sammanfattning : High nitrogen discharge from mining sites has been an environmental issue that has been closely studied in the recent years. The environmental effects of high nitrogen discharge are mainly eutrophication, but can also lead to changed species composition and algae blooms. LÄS MER

  2. 2. Tracing the interplay between cellular metabolism and cell cycle

    Författare :Irena Roci; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer cells are more vulnerable to targeting during S-G2-M cell cycle phases due to common deregulations in cell cycle checkpoint mechanisms. Most common cancer drugs target processes in the S-G2-M phases, often causing negative effects on proliferating normal cells. LÄS MER

  3. 3. Exploring disease biomarkers and mechanisms using metabolomics

    Författare :Anna Lindahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A metabolome is the complete set of small molecules or metabolites present in a biological system. It is the result of internal, genetically determined processes, as well as external factors. The metabolome can consequently be seen as an interface between the genome and the environment. LÄS MER

  4. 4. Isotope Ratio and Trace Element Measurements Using Inductively Coupled Plasma – Mass Spectrometry : Method Development and Applications in Environmental Forensics

    Författare :Simon Pontér; Anders Widerlund; Hjalmar Laudon; Luleå tekniska universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Isotope ratio measurements; screening analysis; ICP-MS; MC-ICP-MC; multi-tracer studies; fractionation; Environmental Forensics; Tracing; Tillämpad geokemi; Applied Geochemistry;

    Sammanfattning : Environmental Forensics is a scientific methodology developed for identifying sources, the timing of release, and transport pathways for potentially hazardous environmental contaminants. It combines a variety of analytical methods with principles derived from disciplines such as chemistry, geology, geochemistry, hydrogeology, and statistics, with the purpose to provide objective scientific and legal conclusions on the source and/or time of a contaminant release. LÄS MER

  5. 5. The role of autophagy in anticancer therapy

    Författare :Matheus Dyczynski; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autophagy is a fundamental catabolic process, which is utilized by nearly every cell and tissue type upon stress exposure and has been shown to contribute to resistance to chemotherapy in a variety of cancers. The subject of this thesis is to shed light on the role of autophagy in chemotherapy and to investigate novel regulators of autophagy. LÄS MER