Sökning: "Isomerisation Dynamics"

Hittade 5 avhandlingar innehållade orden Isomerisation Dynamics.

  1. 1. An Ultrafast Spectroscopic and Quantum-Chemical Study of the Photochemistry of Bilirubin : Initial Processes in the Phototherapy for Neonatal Jaundice

    Författare :Burkhard Zietz; Tomas Gillbro; Jouko Korppi-Tommola; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bilirubin; Phototherapy; Neonatal Jaundice; Femtosecond Spectroscopy; CASSCF; TD-DFT; Isomerisation Dynamics; Biophysical chemistry; Biofysikalisk kemi;

    Sammanfattning : Bilirubin is a degradation product of haem, which is constantly formed in allmammals. Increased levels of bilirubin in humans lead to jaundice, a conditionthat is very common during the first days after birth. This neonataljaundice can routinely be treated by phototherapy without any serious sideeffects. LÄS MER

  3. 2. Conformational Dynamics of Rhodopsins Visualized by Time-resolved Wide Angle X-ray Scattering

    Författare :Erik Malmerberg; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Time-resolved wide Angle X-ray Scattering; Retinylidene proteins; Rhodopsin; Bacteriorhodopsin; Proteorhodopsin;

    Sammanfattning : Rhodopsins are a family of light-sensitive proteins found in the cellular membranes of a wide range of living organisms. These membrane proteins share a common molecular architecture and are able to use light energy to perform a variety of different biological functions. LÄS MER

  4. 3. Transient State Fluorescence Microscopy - method development and biological applications : Exploiting the dark states of fluorophores to measure oxygen concentrations, redox state, Förster resonance energy transfer and membrane viscosity

    Författare :Thiemo Spielmann; Jerker Widengren; Karsten König; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transient States imaging TRAST ; Triplet State imaging; fluorescence microscopy; modulated excitation; triplet state; radical state; trans-cis isomerisation;

    Sammanfattning : Due to their long lifetime, triplet, redox and other transient states of fluorophores are highly sensitive to the micro-environment. Imaging their spatial distribution in biological samples can therefore help answer interesting questions about the metabolism, molecular interactions and dynamics in living cells. LÄS MER

  5. 4. EGF-like modules in blood coagulation proteins : Ca²+ binding, module interactions, structure and dynamics as studied by NMR spectroscopy

    Författare :Andreas Muranyi; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; residual dipolar couplings; protein S; factor VII; protein structure; calcium; blood coagulation; NMR spectroscopy; EGF modules; Physical chemistry; Fysikalisk kemi;

    Sammanfattning : Modules are independently folding protein domains defined on the gene level. The epidermal growth factor-like (EGF) modules are involved in protein-protein interactions and are found in numerous membrane proteins and extracellular proteins, including many proteins of the blood coagulation system. LÄS MER

  7. 5. Modelling biomolecular interactions

    Författare :Johan Bredenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Computational chemistry; molecular dynamics; nuclear receptors; force field parameterization; zinc fingers; DNA; proteins.;

    Sammanfattning : Computational approaches for understanding and aiding in molecular biology has increased in significance over the last decades, where a wealth of biochemical experiments have provided a solid ground for developing computer models that can be used to predict unresolved issues within biology. Molecular dynamics (MD) is one of these methods, based on classical laws, and suitable for handling large macromolecules in their natural environment, water. LÄS MER