Sökning: "Islet isolation"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Islet isolation.
1. Standardization of Islet Isolation and Transplantation Variables
Sammanfattning : Currently, the transplantation of islets of Langerhans is a viable means to maintain control of blood sugar levels and reduce the risk of hypoglycemia in defined populations with brittle type I diabetes mellitus or those requiring pancreatectomy. However, the process of islet isolation is highly variable and not all isolations result in islet numbers or quality suitable for transplantation. LÄS MER
2. Islet Transplantation a Technical Challenge : Studies on Human Pancreas Preservation and Enzymatic Digestion
Sammanfattning : Islet transplantation has found its niche in diabetes treatment. It has contributed to a better quality of life and better glycemic control of patients with diabetes suffering from severe hypoglycemia that are not eligible for vascularized pancreas transplantation. Islet isolation is a technically challenging procedure. LÄS MER
3. Formation of Composite Islet Grafts : A novel strategy to promote islet survival and revascularization
Sammanfattning : The islets of Langerhans are small and delicate spheroid organs scattered in the pancreas responsible for insulin production. Transplantation of isolated islets is a beneficial therapy for patients with a severe form of type 1 diabetes. LÄS MER
4. Technical challenges in human islet isolation
Sammanfattning : Transplantation of islets of Langerhans is an effective treatment option for patients with brittle type 1 diabetes mellitus. This treatment restores glucose control and also reduces hypoglycemia. Unfortunately, the outcome from islet isolations is variable, and many preparations do not yield sufficient islet number or islet quality. LÄS MER
5. In vivo imaging of islet cells and islet revascularization
Sammanfattning : Glucose homeostasis depends on the release of insulin from the pancreatic beta-cell. Impaired insulin release is a hallmark of diabetes mellitus. LÄS MER