Sökning: "Isak demirel"

Hittade 2 avhandlingar innehållade orden Isak demirel.

1. 1. Uropathogenic Esherichia coli, multidrug-resistance and induction of host defense mechanisms

   Författare :Isak Demirel; Katarina Persson; Robert Kruse; Mirjana Poljakovic; Gabriela Godaly; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urinary tract infection; uropathogenic Escherichia coli; suppressor of cytokine signalling 3; nitric oxide; cytokines; extended-spectrum beta-lactamases; filamentation; IL-6; Biomedicin; Biomedicine;

   Sammanfattning : Uropathogenic Escherichia coli (UPEC) is the primary cause of urinary tract infection (UTI), which is one of the most common infections in humans. UPEC strains have acquired successful strategies to subvert the host defense and antibiotics to persist in the urinary tract. LÄS MER

3. 2. The role of caspase-1, caspase-4, NLRP3 and IL-1RA in bladder epithelial cells infected by uropathogenic Escherichia coli

   Författare :Anna Lindblad; Isak Demirel; Manisha Yadav; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urinary tract infection; inflammasome; uropathogenic Escherichia coli; NLRP3; caspase-1; caspase-4; IL-1RA; antimicrobial peptides; estrogen;

   Sammanfattning : Urinary tract infection is one of the most common infections and is mostlycaused by uropathogenic Escherichia coli (UPEC). The inflammasomeassociatedproteins caspase-1, caspase-4 and NLRP3 are essential in the hostcell response during urinary tract infection by regulating IL-1β release. LÄS MER