Sökning: "Irene Söderhäll"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Irene Söderhäll.

1. 1. White Spot Syndrome Virus Interaction with a Freshwater Crayfish

   Författare :Pikul Jiravanichpaisal; Kenneth Söderhäll; Irene Söderhäll; Ellen Kauschke; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; WSSV; crayfish; hematopoietic tissue; cytokine; innate immunity; hemocytes; Biologi; Biology; Biologi;

   Sammanfattning : Viruses are very abundant in water and hence diseases caused by viruses are common in marine organisms. These diseases create great problems for the commercial farming of crustaceans and mussels. LÄS MER

3. 2. Regulation of hematopoiesis in the freshwater crayfish, Pacifastacus leniusculus : role of transglutaminase

   Författare :Kingkamon Junkunlo; Irene Söderhäll; Kenneth Söderhäll; Chadanat Noonin; Mats W Johansson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ast1; clotting protein; crayfish; hematopoiesis; PVF PVR; ROS; transglutaminase; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

   Sammanfattning : The freshwater crayfish, Pacifastacus leniusculus, has been used as a model for studying hematopoiesis or blood cell production or hematopoiesis and immunity. The work of this thesis aims to investigate the impact of factors such as ROS signaling, Ast1, and the PVF/PVR signaling pathway in controlling stem cell behavior during hematopoiesis and specifically the role of the crosslinking enzyme transglutaminase (TGase) in regulation of hematopoiesis. LÄS MER

4. 3. Hematopoiesis in a Crustacean

   Författare :Xionghui Lin; Irene Söderhäll; Kenneth Söderhäll; Michael J. Williams; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; astakine; cytokine; hematopoiesis; prokineticin; transglutaminase; ATP synthase; innate immunity; apoptosis; Immunology; Immunologi; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

   Sammanfattning : Hemocytes (blood cells) play an important role in the immune response in invertebrates, and thus the regulation of hemocyte homeostasis (hematopoiesis) is essential for the host survival against pathogens. Astakine 1, a homologue to vertebrate prokineticins, was first identified in the freshwater crayfish Pacifastacus leniusculus as a cytokine, and was found to be necessary for new hemocyte synthesis and release in vivo, and also to induce spreading and proliferation of Hematopoietic tissue cells (Hpt cells, precursor of hemocytes) in vitro. LÄS MER

5. 4. Functional Studies of Some Immune Relevant Genes in a Crustacean

   Författare :Haipeng Liu; Kenneth Söderhäll; Irene Söderhäll; Lage Cerenius; Ingrid Faye; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; anti-LPS factor; crayfish; hemocyte; innate immunity; melanization; phenoloxidase; RNA interference; WSSV; Biology; Biologi;

   Sammanfattning : The freshwater crayfish, Pacifastacus leniusculus, mounts a strong innate immune response against microbes such as viruses and bacteria. In this thesis, a novel RNA interference (RNAi) method mediated with histone H2A was developed and applied in crayfish hematopoietic tissue cell cultures for gene functional studies. LÄS MER

7. 5. Melanization and Hemocyte Homeostasis  in the Freshwater Crayfish, Pacifastacus leniusculus

   Författare :Chadanat Noonin; Irene Söderhäll; Kenneth Söderhäll; Smith Valerie; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; melanization; prophenoloxidase; caspase; hematopoiesis; thymosin; astakine; circadian rhythm; reactive oxygen species; tyrosinase; prokineticin;

   Sammanfattning : Blood cells or hemocytes play important roles in immunity. They are a major source of many immune-related molecules such as antibodies in adaptive immunity of vertebrates and prophenoloxidase (proPO) in invertebrates. LÄS MER