Sökning: "Invasion"

Visar resultat 11 - 15 av 423 avhandlingar innehållade ordet Invasion.

  1. 11. Modeling glioblastoma growth patterns and their mechanistic origins

    Författare :Emil Rosén; Sven Nelander; Rebecka Jörnsten; Philip Gerlee; Kristin Swanson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; glioblastoma; invasion; image analysis; neural networks; Mathematics with specialization in Applied Mathematics; Matematik med inriktning mot tillämpad matematik; Oncology; Onkologi; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Glioblastoma (GBM) is the most common and aggressive primary brain cancer. GBM cells migrate away from the primary lesion and invade healthy brain tissue. The invading cells escape surgical resection, radiotherapy and develop resistance to chemotherapy. Consequently, despite treatment, recurrence is inevitable, and survival is only 14 months. LÄS MER

  2. 12. Vaginal commensal bacteria. Interactions with cervix epithelial and monocytic cells and influence on cytokines and secretory leukocyte protease inhibitor, SLPI

    Författare :Louise Strömbeck; Göteborgs universitet; []
    Nyckelord :Prevotella bivia; bacterial vaginosis BV ; invasion; Lactobacillus; secretory leukocyte protease inhibitor SLPI ; cytokines; THP-1; HeLa cells;

    Sammanfattning : Vaginal commensal bacteria Interactions with cervix epithelial and monocytic cells and influence on cytokines and secretory leukocyte protease inhibitor, SLPI Louise Strömbeck Department of Infectious Medicine, Gothenburg University Abstract Lactobacillus is the predominant species of the vaginal microbiota in women of childbearing age. Lactobacilli are thought to contribute to the local immune defence by producing a variety of antimicrobial substances and, thereby, attenuate growth of other opportunistic bacteria. LÄS MER

  3. 13. TRAF6 stimulates TGFβ-induced oncogenic signal transduction in cancer cells

    Författare :Shyam Kumar Gudey; Marene Landström; Urban Lendahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; c-Jun; invasion; non-Smad; Notch; NICD; oncogenesis; presenilin1; PKCζ; prostate cancer; p21; p38; p300; Snail1; TGFβ; TβRI; TACE; TRAF6; ubiquitination; TGFbeta signal transduction; Pathology; patologi;

    Sammanfattning : Prostate cancer is one of the leading causes of cancer-related deaths in men worldwide, with 10,000 new cases/year diagnosed in Sweden. In this context, there is an urgent need to identify new biomarkers to detect prostate cancer at an initial stage for earlier treatment intervention. LÄS MER

  4. 14. Understanding the adaptive capacity of the bumblebee Bombus terrestris across native and novel environments

    Författare :Cecilia Hjort; Biodiversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bumblebees; Bombus terrestris; Pollination; Introgression; Single nucleotide polymorphisms; Whole Genome Sequencing; Landscape simplification; Gene flow; Morphology; Environmental variation; Invasion; Local adaptation; Island;

    Sammanfattning : Anthropogenic stressors such as agricultural intensification, climate change, andincreased densities of non-native managed bees used for crop pollination arecontributing to bee declines. Understanding how and why bees have responded topast environmental changes is crucial for predicting future ones and enablingmitigation to maintain the functioning of both natural and agricultural ecosystems. LÄS MER

  5. 15. Chicagoskolan : Institutionaliseringen, idétraditionen och vetenskapen

    Författare :Oscar Andersson; Socialantropologi; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; cities in the city; melting pot; race relation cycle; natural area; natural history; migration; marginal man; life history; invasion; hybrid; hobo; ghetto; ecology; Chicago School; disorganization; succession; transit and urbanization; Sociology; Sociologi;

    Sammanfattning : The main purpose of my thesis is to investigate how the Chicago School in urban sociology, that was active between 1915 and 1935, developed and why it produced so many classical monographs during a period of about ten to fifteen years. To outline the historical reasons for the School to develop I have chosen to view the historical context as a field with different actors. LÄS MER