Sökning: "Intravenous drug use"

Visar resultat 21 - 25 av 28 avhandlingar innehållade orden Intravenous drug use.

  1. 21. HIV Persistence and Viral Reservoirs

    Författare :Arvid Edén; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; antiretroviral therapy; latency; cerebrospinal fluid; central nervous system; efavirenz; lopinavir; atazanavir; neopterin; viral decay;

    Sammanfattning : Although antiretroviral therapy (ART) can effectively inhibit replication of human immunodeficiency virus type 1 (HIV-1), the virus is able to persist in cellular and anatomical viral reservoirs. Latently infected resting memory CD4+ T-cells are an important cellular reservoir, and the central nervous system (CNS) an important anatomical reservoir for HIV-1 infection. LÄS MER

  3. 22. Pain in patients with osteoarthritis treated with total knee arthroplasty

    Författare :Henrik Lundblad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :pain;

    Sammanfattning : Background: The pathogenesis and mechanisms of pain in osteoarthritis (OA) are virtually unknown. In the absence of specific and effective pharmacological treatment, joint replacement often remains the only option. Total knee arthroplasty (TKA) has a significant effect in terms of pain relief. LÄS MER

  4. 23. Staphylococcus aureus bacteraemia and endocarditis : epidemiology, short- and long-term mortality

    Författare :Hilmir Ásgeirsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Staphylococcus aureus is a major cause of bloodstream infections and endocarditis. S. aureus bacteraemia (SAB) is associated with substantial morbidity and mortality, and endocarditis is a severe complication. Population-based studies on S. LÄS MER

  5. 24. Ecological impact of antibiotic treatment on human normal microflora

    Författare :Mamun-Ur Rashid; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ceftobiprole;

    Sammanfattning : The skin and the mucosal surfaces of humans are colonized with microorganisms which are often referred as the normal microflora. There is a biological balance between the human host and the normal microflora in health. The extensive use of antibiotics in both humans and animals has caused the development of many resistant bacteria. LÄS MER

  7. 25. HIV/HCV co-infection in Sweden : epidemiology, HCV treatment and the importance of IL28B gene polymorphism

    Författare :Jenny Stenkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Liver disease, mainly due to hepatitis C virus (HCV) infection, is a leading cause of death in HIV positive patients with access to antiretroviral therapy (ART). HCV treatment, which can prevent long-term complications of HCV infection, is available. Despite this, only a minority of HIV/HCV co-infected patients initiate HCV treatment. LÄS MER