Sökning: "Intrathecal baclofen"

Hittade 5 avhandlingar innehållade orden Intrathecal baclofen.

  1. 1. What makes a patient satisfied with intrathecal baclofen treatment for spasticity : Expectations and experiences

    Författare :Stina Gunnarsson; Kersti Samuelsson; Dag Lemming; Siw Alehagen; Björn Gerdle; Anna Danielsson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Interview; Intrathecal baclofen; Multivariate analyses; Occupational performance; Optimism; Pain intensity; Preexpectations; Satisfaction; Self-efficacy; Spasticity.;

    Sammanfattning : Patients often report reduced spasticity and/or pain, improved function and comfort, and a high level of satisfaction after treatment with intrathecal baclofen (ITB). However, dissatisfaction, complications and unmet goals are also reported. LÄS MER

  3. 2. Drug-enhanced spinal cord stimulation for neuropathic pain : studies on neurochemical mechanisms and clinical applications

    Författare :Gastón Schechtmann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acetylcholine; baclofen; cholinergic analgesia; clonidine; gabapentin; neuropathic pain; nerve injury; pregabalin; spinal cord stimulation; intrathecal drug;

    Sammanfattning : Spinal cord stimulation (SCS) is an effective surgical treatment for neuropathic pain refractory to pharmacological therapy. For many patients suffering from this type of chronic pain, SCS is in fact the ultimate treatment option. LÄS MER

  4. 3. Treatment of pain behavior after spinal cord injury in rats with special emphasis on the role of adenosine receptors

    Författare :Margareta von Heijne; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :adenosine; adenosine receptors; allodynia; baclofen; central pain; clonidine; intrathecal; morphine; neuropathic pain; opioid; rat; R-phenylisopropyladenosine; spinal cord injury; tolerance;

    Sammanfattning : Central pain is a form of neuropathic pain occurring after injury or dysfunction in the central nervous system, including the spinal cord. Allodynia (pain to innocuous stimuli) to mechanical and cold stimulation is a common feature of central pain and it is often resistant to treatment. LÄS MER

  5. 4. Advances in spinal cord stimulation : enhancement of efficacy, improved surgical technique and a new indication

    Författare :Göran Lind; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :spinal cord stimulation;

    Sammanfattning : Introduction and aim: Spinal cord stimulation (SCS) has been used for treatment of otherwise therapy-resistant chronic neuropathic pain for about four decades. However, 30-40 % of the patients do not benefit from SCS, despite careful case selection and technical advances. LÄS MER

  7. 5. Spinal cord stimulation in neuropathy : experimental studies of biochemistry and behaviour

    Författare :Jian-Guo Cui; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neuropathic pain; mononeuropathy; GABA; glutamate; aspartate; galanin; neuropeptide Y; adenosine; spinal cord stimulation;

    Sammanfattning : Neuropathic pain, presenting with cutaneous hypersensitivity, i.e. allodynia, dysesthesia and hyperalgesia, is often difficult to manage with pharmacotherapy, but may be effectively alleviated by electric spinal cord stimulation (SCS). However, the mode of action of SCS is still poorly understood. LÄS MER