Sökning: "Intrathecal administration"
Visar resultat 1 - 5 av 19 avhandlingar innehållade orden Intrathecal administration.
1. Studies of the Biology of Intrathecal Treatment in Progressive MS
Sammanfattning : Background: Multiple Sclerosis (MS) is a chronic, inflammatory, autoimmune disease, affecting the central nervous system (CNS). About 85% of afflicted present with a relapsing-remitting form of the disease (RRMS), for which a breakthrough in treatment was made in 2008 with rituximab, an antibody directed towards CD20, a surface antigen on B-cells. LÄS MER
2. Neuroinflammation and pain
Sammanfattning : ABSTRACT Background: Persistent pain that remains long after the physiological trigger has been resolved is a disabling condition. A possible mechanism for the transition from acute physiological pain to persistent pain involves low-grade inflammation in the central nervous system, in which inflammatory-activated astrocytes play a significant role. LÄS MER
3. Adenosine analogues for antinociception : experimental studies in rodents on peripheral and intrathecal drug administration including assessment of spinal cord neurotoxicity
Sammanfattning : .... LÄS MER
4. Postoperative pain management - predictors, barriers and outcome
Sammanfattning : Despite the availability of clinical practice guidelines, effective analgesics and new technologies for drug administration, the management of postoperative pain continues to remain problematic and unsatisfactory. Nurses play an important role in the pain management. LÄS MER
5. Intrathecal adenosine for treatment of acute pain : safety assessments and evaluation in experimental, surgical and labour pain
Sammanfattning : Adenosine is an endogenous compound present in all cells in the body with a wide range of physiological effects. Exogenous administration of adenosine is used clinically as an antiarrytmic agent and as a vasodilator. LÄS MER