Sökning: "Intra-Articular"

Visar resultat 1 - 5 av 39 avhandlingar innehållade ordet Intra-Articular.

  1. 1. Intra-articular Glucocorticoid Treatment : Efficacy and Side Effects

    Författare :Tomas Weitoft; Lars Rönnblom; Ronald vanVollenhoven; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; arthritis; intra-articular glucocorticoid; triamcinolone hexacetonide; arthrocentesis; bone metabolism; cartilage; cortisol; ACTH; joint infection; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Intra-articular glucocorticoid injection therapy is frequently used to relieve symptoms of arthritis, but there is considerable variation in injection routines among physicians. One issue of debate concerns the importance of synovial fluid aspiration during the injection procedure. LÄS MER

  3. 2. Articular distension in arthroscopy : an experimental study on intra- and extra-articular effects of pressure

    Författare :Anders Sperber; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Arthroscopy; intra-articular pressure; in vivo measurements; knee joint capsule; tensile properties; stress-strain; multicompartmental pressures; lower leg venous blood flow; ultrasound; acromioplasty; intra-muscular pressure; fluid absorption; shoul;

    Sammanfattning : The purpose of this thesis was to analyse the effects of various intra-articular pressures (IAP) on soft tissues and to provide guidelines for the choice of safe infusion pressures during arthroscopy. The tensile properties of the knee-joint capsule were recorded from stress-strain-relaxation tests within 170 mmHg IAP. LÄS MER

  4. 3. Neuropeptides in temporomandibular joint arthritis

    Författare :Anna Appelgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adjuvant; Arthritis; Calcitonin gene-related peptide; Glucocorticosteroids; Hippocampus; Hyperalgesia; Hypothalamus; Hypothalamo-pituitary-adrenal axis; Intra-articular temperature; Neurokinin A; Neuropeptides; Neuropeptide Y; Nociception; Pain; Pituitary; Pressure pain threshold; Rheumatoid arthritis; Substance P; Synovial fluid; Temporomandibularjoint; Visual analog scale;

    Sammanfattning : Involvement of the peripheral and central nervous systems in the pathophysiology of arthritis has been suggested and neuropeptides are thought to participate in the mediation and modulation of the inflammatory process. The main objective of the clinical studies was to investigate the relationship between the presence of neuropeptides in the synovial fluid of the temporomandibular joint (TMJ) and the stomatognathic symptoms and signs, including the intra-articular temperature (IAT), in patients with TMJ arthritis. LÄS MER

  5. 4. Post-translational and therapy-induced modifications in rheumatoid arthritis

    Författare :Dimitrios Makrygiannakis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial proliferation and excessive mononuclear infiltration leading to destruction of bone and cartilage, with subsequent joint deformities and physical disability. Even though RA etiology is still unknown, autoantibody driven pathogenic mechanisms are considered to be important, with strong evidence for the pathogenic potentials of antibodies directed against citrullinated antigens. LÄS MER

  7. 5. Synovial metabolism after different degrees of trauma : effects of pharmacological and physiological intervention : a microdialysis study of the knee joint synovium

    Författare :Anders Stålman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Knee arthroscopy is one of the most common orthopedic procedures. Postoperative pain and knee swelling is often a problem. Optimal pain management in knee arthroscopic procedures is important to permit same-day discharge and to contribute to early mobilisation, reduced cost and increased patient satisfaction. LÄS MER