Sökning: "Interspecies hybridization"

Hittade 2 avhandlingar innehållade orden Interspecies hybridization.

1. 1. Growth and Behaviour : Epigenetic and Genetic Factors Involved in Hybrid Dysgenesis

   Författare :Wei Shi; Reinald Fundele; Diethard Tautz; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Interspecies hybridization; hybrid dysgenesis effect; speciation; genomic imprinting; epigenetics; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

   Sammanfattning : In mammals, the most frequently observed hybrid dysgenesis effects are growth disturbances and male sterility. Profound defects in placental development have been described and our work on hybrids in genus Mus has demonstrated putative hybrid dysgenesis effects that lead to defects in lipid homeostasis and maternal behavior. LÄS MER

3. 2. Molecular Mechanisms Underlying Abnormal Placentation in the Mouse

   Författare :Yang Yu; Reinald H. Fundele; Rolf Ohlsson; J. GRAHAM BURTON; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; IUGR; Placental phenotype; Placental hyperplasia; Diabetes; IHPD; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

   Sammanfattning : Placental development can be disturbed by various factors, such as mutation of specific genes or maternal diabetes. Our previous work on interspecies hybrid placental dysplasia (IHPD) and two additional models of placental hyperplasia, cloned mice and Esx1 mutants, showed that many genes are deregulated in placental dysplasia. LÄS MER