Sökning: "Interleukin"

Visar resultat 1 - 5 av 584 avhandlingar innehållade ordet Interleukin.

  1. 1. Effects of Interleukin-4 and Interleukin-13 on Bone

    Författare :Carl-Johan Silfverswärd; Olle Nilsson; Östen Ljunggren; Kenneth Jonsson; Li Felländer-Tsai; Uppsala universitet; []
    Nyckelord :Medicine; Bone; Osteoblasts; Interleukin-4; Interleukin-13; Knockout; Medicin;

    Sammanfattning : Cytokines play important roles in bone metabolism, participating in the complex interplay necessary for normal bone formation and turnover. The aim of the present thesis was to investigate the effects of two anti-inflammatory cytokines, interleukin-4 (IL-4) and interleukin-13 (IL-13) on bone. LÄS MER

  3. 2. Interleukin 15 and 17 in Staphylococcus aureus arthritis

    Författare :Louise Henningsson; Göteborgs universitet; []
    Nyckelord :Staphylococcus aureus; Interleukin-17A; Interleukin-15; arthritis; osteoclasts; IL-23;

    Sammanfattning : Staphylococcus aureus–induced arthritis leads to severe joint destruction and high mortality despite antibiotic treatment. Thus, there is a need to identify new treatment targets in addition to antibiotic therapy. Interleukin (IL)-15 has been implicated both in osteoclastogenesis and in bacterial clearance – two important issues in S. LÄS MER

  4. 3. Interleukin-17 in models of neutrophilic lung disease

    Författare :Stefan Ivanov; Göteborgs universitet; []
    Nyckelord :Interleukin-17; Interleukin-23; Matrix metalloproteinase-9; neutrophils; macrophages; CD4 cells; innate response; lungs;

    Sammanfattning : Several acute or chronic lung disorders like adult respiratory distress syndrome, acute severe asthma, chronic obstructive pulmonary disease, chronic lung allograft rejection and cystic fibrosis, are associated with signs of an excess innate response in the bronchoalveolar space. Neutrophils may play a pathogenic role in these lung diseases by contributing to non-specific bronchial hyperresponsiveness and bronchial hypersecretion, as well as to epithelial damage and tissue remodelling. LÄS MER

  5. 4. Infectious and inflammatory mechanisms in preterm birth and cerebral palsy

    Författare :Bo Jacobsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; preterm birth; preterm labor; preterm prelabor rupture of membranes; intra-uterine infection; intra-amniotic inflammation; interleukin-6; interleukin-8; interleukin-18; monocyte chemotactic protein-1; cerebral palsy; antenatal risk factors; chorioamnionitis.;

    Sammanfattning : Background: International studies of women in preterm labor (PTL) and preterm pre-labor rupture of the membranes (pPROM) have shown a significant association between microbial invasion of the amniotic cavity (MIAC), some cytokines and chemokines and preterm birth (PTB). These studies have been performed in countries with higher incidence of PTB than that in Sweden. LÄS MER

  7. 5. Inflammatory cytokines and NFκB in Alzheimer’s disease

    Författare :Linda Fisher; Kerstin Iverfeldt; Illana Gozes; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-amyloid; interleukin-1; interleukin-6; cell-penetrating peptide; PNA; Neurochemistry; Neurokemi;

    Sammanfattning : Alzheimer’s disease is the most common form of dementia. It is a neurodegenerative disorder characterized by extracellular senile plaques and intracellular neurofibrillary tangles. The main constituent of the senile plaques is the neurotoxic β-amyloid peptide. LÄS MER