Sökning: "Interleukin-1 trap"

Hittade 1 avhandling innehållade orden Interleukin-1 trap.

  1. 1. Experimental Studies Aiming to Prevent Type 1 Diabetes Mellitus

    Författare :Tobias Rydgren; Stellan Sandler; Nils Welsh; Adrian Bone; Uppsala universitet; []
    Nyckelord :Cell biology; Diabetes; Interleukin-1 trap; Simvastatin; Nitric oxide synthase; Cytokine; Pancreatic islet; Streptozotocin; Transplantation; Cellbiologi;

    Sammanfattning : Type 1 diabetes mellitus (T1DM) is an autoimmune disease in which T-cells and macrophages invade the islets of Langerhans and selectively destroy the insulin producing β-cells, either directly or through the secretion of e.g. cytokines and nitric oxide (NO). This thesis has studied possible strategies to prevent T1DM. LÄS MER