Sökning: "Interleukin- 1 beta"

Visar resultat 16 - 20 av 45 avhandlingar innehållade orden Interleukin- 1 beta.

  1. 16. Matrix metalloproteases and cell motility in malignant mesothelioma

    Författare :Zhiwen Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Matrix; metalloproteases MMPs ; cell motility; growth factors; malignant mesothelioma; invasion;

    Sammanfattning : Invasion and metastasis of malignant tumor cells requires destruction of and migration through extracellular matrix (ECM) such as basement membrane and interstitial stroma. The ECM-degrading proteases produced by tumor cells and stromal cells and cell motility play a crucial role in this process. LÄS MER

  3. 17. Pain and radiographic changes of the arthritic temporomandibular joint : relation to cytokines in synovial fluid and plasma

    Författare :Silvi Nordahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Arthritis; Bone loss; Interleukin- 1 beta; Pain; Plasma; Progression; Radiographic changes; Synovial fluid; Temporomandibular joint; Tumor Necrosis Factor alpha;

    Sammanfattning : In patients with rheumatoid arthritis and other inflammatory joint diseases, radiographic changes of the TMJ are frequently observed. Common symptoms of TMJ involvement are pain at rest and on movement of the jaw. LÄS MER

  4. 18. Studies on uptake and effect of triclosan on production of inflammatory mediators in human gingival fibroblasts

    Författare :Manal Mustafa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Triclosan; gingival fibroblasts; IL-beta; IFN-gamma; MHC class II; PGE2; mPGES-1;

    Sammanfattning : Triclosan (2,4,4'-trichloro-2'-hydroxy-diphenyl ether) is a lipid soluble anti-bacterial agent widely used in dentifrices, mouthrinses, soap and cosmetics. Although reports on the efficacy of triclosan on periodontal diseases are conflicting, it is documented in clinical studies that dentifrices containing triclosan reduce plaque accumulation and improve gingival health. LÄS MER

  5. 19. Mechanisms influencing activation and survival of normal and malignant lymphoid cells in the testis

    Författare :Mikael von Euler; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acute lymphoblastic leukaemia; testis; cytokines; IL-1; TGFbeta;

    Sammanfattning : Acute lymphoblastic leukaemia (ALL) is the most common childhood malignancy and the testis is the third most common site of relapse after treatment. Testicular function is regulated by pituitary hormones, but the testicular microenvironment is also locally regulated through cell-cell interactions and by paracrine factors. LÄS MER

  7. 20. Cytokines and cytokine-directed intervention in experimental arthritis

    Författare :Karin Palmblad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :pro-inflammatory cytokines; collagen-induced arthritis; CNI-1493; HMG-1;

    Sammanfattning : Rheumatoid arthritis (RA) is a common chronic autoimmune and inflammatory disease. Although the etiology of RA remains unknown, a general understanding of the pathogenesis is steadily increasing. The macrophage products tumor necrosis factor (TNF) and interleukin 1 (IL-1) are recognized as pivotal mediators in the arthritic process. LÄS MER