Sökning: "Interleukin- 1 beta"

Visar resultat 11 - 15 av 45 avhandlingar innehållade orden Interleukin- 1 beta.

  1. 11. Genetic polymorphism and natural killer cell activity in multiple myeloma

    Författare :Chengyun Zheng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple Myeloma (MM) is a B cell malignancy characterised by an accumulation of clonal neoplastic plasma cells in bone marrow. Its aetiology remains unknown. Remarkable racial differences in the incidence of MM and occurrence of familial MM suggest that genetic factors may play a role in the development of MM. LÄS MER

  3. 12. Mechanisms of inflammatory lung injury : Studies in isolated perfused rat lungs

    Författare :Anders Ljungman; Östergötlands Läns Landsting; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Isolated perfused rat lungs (IPRLs) were used to study mechanisms andmediators of lung injury due to (i) ischemia-reperfusion (IR) and (ii) endotoxin. To investigate the role of polymorphonuclear neutrophils (PMNs) in IR injury, PMNs were added to the perfusate of IPRLs subjected to IR. LÄS MER

  4. 13. Cardiovascular effects of short-term exposure to air pollution : exploring potential pathways and susceptible subgroups

    Författare :Petter Ljungman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiovascular disease is the most common cause of mortality globally, with a number of contributing risk factors. Ambient air pollution represents a universally present risk factor with a substantial preventive potential. LÄS MER

  5. 14. Studies of cytokine mediated regulation of central nervous functions : role of prostaglandins

    Författare :Monica Ek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :interleukin-1; prostaglandin E2; central nervous system; HPA axis; fever; vagus nerve;

    Sammanfattning : The communication between the immune system and the central nervous system (CNS) results in an array of centrally regulated illness responses, including fever and increased hypothalamus-pituitary-adrenal (HPA) axis activity. The mechanisms by which the immune system signals the brain across the blood-brain barrier have not been completely elucidated, but proinflammatory cytokines, like interleukin-1 (IL-1), are believed to act as important mediators. LÄS MER

  7. 15. Occupational exposure to polycyclic aromatic hydrocarbons and early biomarkers related to cardiovascular disease and cancer

    Författare :Ayman Alhamdow; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Polycyclic aromatic hydrocarbons (PAH) are omnipresent environmental pollutants composed of fused benzene rings and mainly produced by incomplete combustion of organic material. PAH exposure has been associated with increased risk of cancer and probably cardiovascular disease (CVD). LÄS MER