Sökning: "Innate Immunity"

Visar resultat 6 - 10 av 329 avhandlingar innehållade orden Innate Immunity.

  1. 6. Epidermal Reactions to Injury with Implications for Innate Immunity

    Författare :Markus Roupé; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Innate immunity; epidermis; Wound healing; interleukin-8; Antimicrobial peptides;

    Sammanfattning : Abstract The epidermis is one of our primary interfaces towards the external milieu. Following injury, the physical barrier function of the skin is destroyed and the epidermis is left vulnerable to microbial invasion. LÄS MER

  3. 7. Eco-immunological studies of innate immunity in Mallards (Anas platyrhynchos)

    Författare :Anu S. Helin; Jonas Waldenström; Edwin Veldhuizen; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Avian β-defensins AvBDs ; Avian gene expression; Host-pathogen interactions; Innate immunity; Mallard Anas platyrhynchos ; Myxovirus resistance gene Mx ; Retinoic acid inducible gene 1 RIG-I ; Avian β-defensins AvBD ; Genuttryck; Gräsand Anas platyrhynchos ; Immunförsvar; Immungener; Myxovirus resistant gene Mx ; Patogen; Retinoic acid inducible gene 1 RIG-I ; Ecology; Ekologi;

    Sammanfattning : This thesis comprises two sections, both of which explore eco-immunology of the innate immune system of mallards (Anas platyrhynchos). The innate immune system serves a pivotal role as the first line of defense against invading pathogens, and is comprised of physical and chemical barriers. LÄS MER

  4. 8. Regulatory aspects of innate immune responses

    Författare :Ahmed El Marghani; Per-Erik Olsson; Peter Kjellén; Muhammad Zafarullah; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Innate immunity; TOM1L1; inflammatory responses; Biology; Biologi;

    Sammanfattning : Activation of innate immunity is regulated by a variety of signaling molecules within the immune cells. The present thesis was aimed to improve our understanding of innate signaling mechanism and their possible use as bio-indicators of exposure and disease. LÄS MER

  5. 9. Microbe-induced apoptosis in phagocytic cells and its role in innate immunity

    Författare :Robert Blomgran; Olle Stendahl; Limin Zheng; Boris Zhivotovsky; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; cell death; inflammation; innate immunity; microbiology; neutrophil; macrophage; phagocyte; Medical microbiology; Medicinsk mikrobiologi;

    Sammanfattning : Apoptosis, or programmed cell death, is a controlled process by which aged or damages cells are eliminated in multicellular organisms. Neutrophils, short-lived phagocytes of the innate immune system, are highly equipped effectors that can sense, locate, ingest and kill bacterial pathogens. LÄS MER

  7. 10. Influence of host genetics on innate immunity and susceptibility to urinary tract infection

    Författare :Bryndis Ragnarsdottir; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; IRF3; Innate Immunity; urinary tract infections; acute pyelonephritis; asymptomatic bacteriuria; Toll-like receptor 4; CXCR1; TLR4 adaptors; polymorphisms;

    Sammanfattning : It has been known for a long time that the clinical manifestations of urinary tract infections (UTI) differ markedly between individuals, ranging from a sometimes beneficial, asymptomatic state to life threatening infections. This variability in clinical manifestation can be explained in part by the arsenal of virulence factors of the bacteria but the predisposition of the patient is equally important. LÄS MER