Sökning: "Inhibition"

Visar resultat 16 - 20 av 2339 avhandlingar innehållade ordet Inhibition.

  1. 16. Development and preclinical assessment of novel therapies for Epilepsy. Exploring the potential of human-derived cell lines and glial cell line-derived neurotrophic factor for network inhibition

    Författare :Eliska Waloschkova; Epilepsicentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epilepsy; epileptogenesis; inhibition; cell therapy; GABAergic interneurons; mesenchymal stem cells; GDNF;

    Sammanfattning : Epilepsy is one of the leading neurological disorders affecting not only patients who suffer from seizures but also people around them and society in general. The striking one third of patients not responding to pharmacological treatments implies the necessity of developing alternative options for controlling seizures in these individuals. LÄS MER

  3. 17. Platelet Inhibition and Bleeding in Coronary Artery Bypass Surgery

    Författare :Ulrica Alström; Elisabeth Ståhle; Ulf Schött; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bleeding; cardiac surgery; platelet inhibition; re-exploration; cost analysis; Anaesthetics and intensive care; Anestesiologi och intensivvård; Thoraxkirurgi; Thorax Surgery; Anaesthesiology and Intensive Care; Anestesiologi och intensivvård;

    Sammanfattning : A substantial number of patients undergoing cardiac surgery are on dual anti-platelet treatment with clopidogrel and aspirin. A disadvantage with this treatment is increased risk of bleeding. Bleeding is a complication of major concern associated with adverse outcome for the patient and increased hospital resource utilization. LÄS MER

  4. 18. PCR inhibition mechanisms in forensic DNA analysis

    Författare :Maja Sidstedt; Teknisk mikrobiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PCR inhibition mechanisms; Real-time PCR; Digital PCR; Massively parallel sequencing;

    Sammanfattning : In forensic DNA analysis, the polymerase chain reaction (PCR) enables DNAanalysis of minute biological crime scene traces. PCR is an enzymatic reaction for amplification of specific DNA fragments involving both biochemical andbiophysical processes. The main analytical challenge is posed by the nature of the samples of interest. LÄS MER

  5. 19. The Role of Inhibitory Control and Executive Functioning in Hyperactivity/ADHD

    Författare :Lisa Berlin; Erland Hjelmquist; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Psychology; ADHD; hyperactivity; inhibition; executive functioning; development; Psykologi; Psychology; Psykologi; Psychology; psykologi;

    Sammanfattning : This thesis examined inhibition, executive functioning and their possible relation to childhood problems of hyperactivity and inattention, in its clinical form referred to as Attention Deficit Hyper-activity Disorder (ADHD). Concurrent as well as longitudinal relations were of interest, and both clinical and non-clinical samples were studied. LÄS MER

  7. 20. Physiology and Pharmacology of GABAA receptors: The Brakes in the Brain

    Författare :Catarina Lindquist; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; Fysiologi; Ion channels; GABA; Inhibition;

    Sammanfattning : Inhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). LÄS MER