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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Molecular Characterization of Diffuse Large B-cell Lymphoma and Aspects of Transformation

   Författare :Mattias Berglund; Gunilla Enblad; Svetlana Lagercrantz; Christer Sundström; Catharina Larsson; Ingemar Ernberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Diffuse large B-cell lymphoma; Hodgkin lymphoma; follicular lymphoma; transformation; comparative genomic hybridization; prognosis; Onkologi; Oncology; Onkologi;

   Sammanfattning : Lymphomas are a heterogeneous group of neoplasias originating from B- or T-lymphocytes. In this thesis, we determined the genetic and immunophenotypic characterization of DLBCL and their prognostic impact. LÄS MER

3. 2. Metastatic Mechanisms in Malignant Tumors

   Författare :Linda Bojmar; Per Sandström; Olle Stål; Marie Larsson; Ingemar Ernberg; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The ultimate cause of cancer related deaths is metastasis. This thesis is about three of the main human cancers; breast, colorectal and pancreatic cancer, that together account for more than 25% of the cancer-related deaths worldwide. LÄS MER

4. 3. Apoptosis regulation in bladder cancer and multiple sclerosis

   Författare :Gun Jönsson; Ingemar Ernberg; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : .... LÄS MER

5. 4. Glioma as an Ecosystem : Studies of Invasion, Onco-miR Addiction and Mast Cell Infiltration

   Författare :Jelena Põlajeva; Bengt Westermark; Ingemar Ernberg; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioblastoma; mast cell; miR-21; RAP1; CXCL12; SOX2;

   Sammanfattning : Despite recent advances in oncology and extensive research efforts, gliomas remain essentially incurable. Glioblastoma multiforme (GBM, WHO grade IV) is the most common glioma and may arise de novo or progress from a lower-grade lesion. GBM is characterized by invasive growth, aberrant angiogenesis and necrosis. LÄS MER

7. 5. Cellular proteins binding to the HCV 5' and 3' UTRs

   Författare :Karin Spångberg; Ingemar Ernberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Hepatitis C virus; RNA-binding proteins; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

   Sammanfattning : Hepatitis C virus (HCV) is a worldwide health problem with more than 170 million people infected by the virus. About 80% become chronic carriers, which may result in hepatocellular carcinoma. The lack of an in vitro cell culture system that allows propagation of the virus has hampered the development of a vaccine or anti-viral drugs against HCV. LÄS MER