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1. Imported infections’ importance : global change driving Dengue dynamics
Sammanfattning : Background Dengue is a significant problem of international health concern. According to the World Health Organization in 2012, globally, dengue is “the most important mosquito borne viral disease” with incidence 30 higher than it had been 50 years ago. LÄS MER
2. Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations
Sammanfattning : The complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. LÄS MER
3. Staphylococcus aureus bacteremia. Serological findings, phenotypic and genotypic characteristics of S. aureus strains
Sammanfattning : The diagnosis of S. aureus infections is most often based on culture of the organism from various body sites. However, cultures could be false negative due to e.g. LÄS MER
4. Pathogen-host interactions at the surface of Streptococcus pyogenes
Sammanfattning : The bacterial surface can be thought of as the interface where pathogenic bacteria encounter the human host. Interactions between bacterial surface proteins and human proteins are important determinants of the eventual outcome of infection. LÄS MER
5. Interactions between streptococcal M proteins and human plasma proteins
Sammanfattning : Streptococcus pyogenes is a common human pathogen, which causes a variety of diseases. A major virulence factor of S. pyogenes is the surface-associated M protein, which mediates resistance to phagocytosis. Several studies indicate that M proteins inhibit complement deposition and thereby phagocytosis. LÄS MER