Sökning: "Induction"
Visar resultat 21 - 25 av 1752 avhandlingar innehållade ordet Induction.
21. Regulation of morphogen signalling during neural patterning in the Xenopus embryo
Sammanfattning : Morphogens such as Hedghog, Wnt, FGF, and retinoic acid are important signals whose concentrations need to be tightly regulated in the vertebrate embryo to ensure body axis development and formation of the central nervous system. We first show that the intracellular cytoplasmic protein XSufu acts as a dual regulator of Hedgehog (Hh) and Wnt signals during neural induction and patterning in the Xenopus embryo. LÄS MER
22. Interstrand Crosslinks - Induction and repair
Sammanfattning : DNA crosslinking agents exhibit a variety of DNA lesions, such as monoadducts, DNA-DNA interstrand or intrastrand crosslinks or DNA-protein crosslinks. Agents that produce interstrand crosslinks (ICLs) exist naturally and are widely used in chemotherapy. Therefore, it is important to understand how the lesions induced by these agents are repaired. LÄS MER
23. Tertiary lymphoid structures in glioblastoma : Discovery, Characterization and Therapeutic Induction
Sammanfattning : Glioblastoma (GBM) is an incurable brain cancer with a median survival of less than two years from diagnosis. The tumor microenvironment plays a major role in GBM progression through sustaining immunosuppression and poor lymphocytic infiltration. LÄS MER
24. Plasma Interactions with Icy Bodies in the Solar System
Sammanfattning : Here I study the “plasma interactions with icy bodies in the solar system”, that is, my quest to understand the fundamental processes that govern such interactions. By using numerical modelling combined with in situ observations, one can infer the internal structure of icy bodies and their plasma environments. LÄS MER
25. Effect of thimerosal on the murine immune system : especially induction of systemic autoimmunity
Sammanfattning : The organic mercury compound ethylmercurithiosalicylate (thimerosal), an antiseptic and a preservative, has recently raised public health concern due to its presence in vaccines globally. Thimerosal dissociates in the body to thiosalicylate and ethyl mercury (EtHg), which is partly converted to inorganic mercuric mercury (Hg2+). LÄS MER