Sökning: "Inactivated"
Visar resultat 6 - 10 av 159 avhandlingar innehållade ordet Inactivated.
6. The role of the tumor suppressor gene, FBW7, and mechanisms of its inactivation in cancer
Sammanfattning : The F-box protein FBW7 is a tumor suppressor and SCF ubiquitin ligase targeting several key oncoproteins for proteasomal degradation. In this thesis we addressed whether the FBW7 gene is inactivated by mutations in various human tumor types and explored alternative mechanism(s) for the inactivation of FBW7. LÄS MER
7. Ammonia sanitisation of human excreta : treatment technology for production of fertiliser
Sammanfattning : Safe reuse of plant nutrients from human excreta increases the sustainability of society and promotes health, both by decreasing disease transmission and by increasing agricultural production. This thesis examined ammonia sanitisation as a treatment method to produce a hygienically safe fertiliser from source-separated urine and faeces. LÄS MER
8. Virus inactivation : evaluation of processes used in biowaste management
Sammanfattning : Animal by-products (ABP) Category 3 includes hatchery waste, and also slaughterhouse waste and manure, aimed for use in biogas production. In order to be used as fertilisers, they must be sanitised to reduce pathogenic microorganisms. The initial European regulations regarding processing standards for ABP intended for use in e.g. LÄS MER
9. Leukotriene A4 hydrolase : exploration of the active sites and catalytic mechanisms by site-directed mutagenesis
Sammanfattning : Leukotriene (LT) A4 is a pivotal intermediate in the biosynthesis of leukotrienes, a family of potent lipid mediators involved in a variety of inflammatory and allergic disorders. The bifunctional zinc metalloenzyme LTA4 hydrolase converts LTA4 into LTB4, one of the most potent chemotaxins known to date. LÄS MER
10. Evaluation of the Rift Valley fever vaccination program in Mozambican cattle
Sammanfattning : Rift Valley fever (RVF) is a viral disease that is spread by various arthropods (primarily mosquitoes) and affects ruminants and humans. RVF has led to tremendous losses of livestock in many African countries, Saudi Arabia, and Yemen, and its zoonotic impact on human deaths has been documented in most of the endemic countries where large outbreaks have occurred. LÄS MER