Sökning: "Inactivated"

Visar resultat 1 - 5 av 147 avhandlingar innehållade ordet Inactivated.

  1. 1. The Role of Innate Immunity in Islet Transplantation : Clinical and Experimental Studies

    Författare :Lisa Moberg; Bo Nilsson; Olle Korsgren; Kristina Nilsson Ekdahl; Rolf Larsson; David Harlan; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; diabetes; islet transplantation; islet of Langerhans; coagulation activation; IBMIR; tissue factor; thrombin; inactivated FVIIa; melagatran; neutrophilic granulocyte; Immunologi; Immunology; Immunologi;

    Sammanfattning : Clinical islet transplantation is an emerging procedure to cure type 1 diabetes. The graft is implanted by infusion into the liver through the portal vein. A major obstacle that still needs to be overcome is the requirement for islets from multiple donors to achieve insulin independence. LÄS MER

  2. 2. Processing of live and heat inactivated Sendai virus for presentation on MHC class I molecules

    Författare :Tianmin Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; antigen presentation; antigen processing; APC; CTL; MHC class1; peptides; Sendai virus; TAP;

    Sammanfattning : PROCESSING OF LIVE AND HEAT INACTIVATED SENDAI VIRUS FOR PRESENTATIONON MHC CLASS I MOLECULES Tianmin Liu Doctoral dissertation from the Microbiology and Tumor Biology Center KarolinskaInstitute, Stockholm, Sweden The present thesis deals with processing of antigens from live and heat inactivatedSendai virus and their loading on MHC class I molecules for presentation to CTL.In paper I it was observed surprisingly that T2 cells (T2 cells transfectedwith H-2Kb), being defective in the expression of TAP peptide transporters, stillpresented Sendai virus antigen on MHC class I molecules to CTL. LÄS MER

  3. 3. Helicobacter pylori infection and immunity. Protection after vaccination and regulation of inflammation in a mouse model

    Författare :Sukanya Raghavan; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; formalin-inactivated H. pylori; post-immunization gastritis; cholera toxin; CD4 CD25 regulatory T cells; CpG ODN;

    Sammanfattning : Helicobacter pylori infection is an important cause of chronic active gastritis and peptic ulcer disease and a risk factor for the development of gastric cancer. An attractive strategy in the control of H. pylori infection is the development of a safe and effective therapeutic vaccine. Using a mouse model of H. LÄS MER

  4. 4. Crosstalk between Inflammation and Coagulation in Acute Pancreatitis - Experimental and Clinical Studies

    Författare :Ellen Andersson; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; acute pancreatitis; active site inactivated factor VII; bleeding; coagulation; factor VII; FVIIai; hemorrhagic complications; hemorrhage; interleukin-6; MIP-2; nuclear factor kappa B; tissue factor;

    Sammanfattning : In various inflammatory conditions a close interplay between inflammation and coagulation is known to exist, where coagulation factor VII (FVII) and tissue factor (TF) are considered to be pivotal players. In this thesis the crosstalk between inflammation and coagulation in acute pancreatitis (AP) has been investigated. LÄS MER

  5. 5. Effects of feeding yeasts on blood physiology and gut microbiota of rainbow trout

    Författare :David Huyben; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []

    Sammanfattning : Yeast represents a sustainable protein alternative to fishmeal in diets for farmed fish, although more than 40% replacement has been shown to reduce fish growth and welfare. This thesis investigated the effects of feeding high inclusions of inactivated and live yeasts to fish in order to replace fishmeal without negative health consequences. LÄS MER