Sökning: "Immunoglobulin Y"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden Immunoglobulin Y.

1. 1. Treatment of Pseudomonas aeruginosa using immunoglobulin Y : A porcine experimental model of ventilator-associated pneumonia and septic shock caused by P. aeruginosa

   Författare :Alexander Otterbeck; Miklós Lipcsey; Michael Haney; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care; Infektionssjukdomar; Infectious Diseases;

   Sammanfattning : Background: Ventilator associated pneumonia (VAP) caused by Pseudomonas aeruginosa is a common cause of morbidity and mortality in patients treated in the intensive care unit. The spread of pathogens with anti-microbial resistance mandates the investigation of novel therapeutic strategies. We hypothesized that specific polyclonal anti-P. LÄS MER

3. 2. Studies of immunoglobulin light chains in rainbow trout (Oncorhynchus mykiss): new insight into the evolution of immunoglobulin genes

   Författare :Sirje Timmusk; Greg Warr; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Immunoglobulin genes; gene organization; evolution; comparative immunology; promoter; rainbow trout Oncorhynchus mykiss ; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär immunologi; Molecular Immunology;

   Sammanfattning : In this thesis, the structure and the expression of immunoglobulin (Ig) light chain genes were studied in rainbow trout and including an evolutionary perspective. A novel Ig light chain locus (IgL2) was identified and characterized. LÄS MER

4. 3. Immunoglobulin isotype switching in health and disease

   Författare :Berivan Baskin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Immunoglobulin isotype switching is the process where the Cmy region, initially located downstream of the VDJ region is replaced by another constant region gene. Class switch recombination takes place between switch (S) regions, composed of tandem repeats of short unit sequences, located 5 of each CH gene, except for Cdelta. LÄS MER

5. 4. Regulation of germline transcription in the immunoglobulin heavy chain locus

   Författare :Jurga Laurencikiene; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : During an immune response, activated B cells develop into high rate immunoglobulin (Ig) secreting plasma cells. They also switch from production of IgM to IgG, IgA or IgE. Specific isotypes of antibodies have functional and structural features that make them particularly well suited to defend against different types of pathogens. LÄS MER

7. 5. Tick-borne encephalitis : on pathogenesis and prognosis

   Författare :Göran Günther; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Human; tick-borne encephalitis; viral; meningo-encephalitis; cerebrospinal fluid; PCR; cytokines; immunoglobulin; SPECT; technetium-99m-HMPAO;

   Sammanfattning : The general aim of the five studies presented in this thesis was to investigate the clinical outcome and prognosis and factors of importance for the pathogenesis of TBE compared to other aseptic meningo-encephalitis. In a prospective study 149 patients presenting with clinical symptoms of acute viral meningo-encephalitis between June 1991 and December 1993 were included. LÄS MER